The original sequence of DNA...

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Question

1. REPLICATION: The original sequence of DNA on the first strand is
Complete its complementary anti-sense NEW strand (2 points)
A T G C G A C C C A A A C C G C A G C A A T T T T T G G G G C T A A T G T A G
2. TRANSCRIPTION: Take the new strand of DNA and code the messenger RNA that would be created from it: (2
points)
1BIOS140 DNA Assignment
3. TRANSLATION: The strand of messenger RNA has the following sequence determine the codons and
polypeptide that will be coded on the ribosome with complementary tRNA (see table on the last page of this
assignment): (2 points)
A U G C G U C C C A A A C C G C A G C A A U U U U U G G G G C U A A U G U A G
4. What is the name of the polypeptide that is being coded by the above sequence (hint: try to GOOGLE it)? What
does it do in the spinal cord and brain? (3 points)
5. Suppose there was a deletion of the second A in the mRNA (see above) what would the resulting polypeptide
look like? (2 points)
A U G C G U C C C A A C C G C A G C A A U U U U U G G G G C U A A U G U A G
6. Why are deletions and frame shift mutations so devastating? (2 points)
7. What causes sickle cell anemia (the changes in the DNA/RNA)? Write the mutation and tell what kind of mutation it
is. (3 points)
2BIOS140 DNA Assignment
3BIOS140 DNA Assignment
8. Describe the role of following structures in protein synthesis
Structure
DNA
mRNA
Ribosome
tRNA
Anticodon
Amino Acid
RNA processing
4BIOS140 DNA Assignment
Role
5BIOS140 DNA Assignm

 

Solution ID:350963 | This paper was updated on 26-Nov-2015

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